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Petchiether A attenuates obstructive nephropathy by suppressing TGF‐β/Smad3 and NF‐κB signalling

Obstructive nephropathy is the end result of a variety of diseases that block drainage from the kidney(s). Transforming growth factor‐β1 (TGF‐β1)/Smad3‐driven renal fibrosis is the common pathogenesis of obstructive nephropathy. In this study, we identified petchiether A (petA), a novel small‐molecu...

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Detalles Bibliográficos
Autores principales: You, Yong‐Ke, Luo, Qi, Wu, Wei‐Feng, Zhang, Jiao‐Jiao, Zhu, Hong‐Jian, Lao, Lixing, Lan, Hui Y., Chen, Hai‐Yong, Cheng, Yong‐Xian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6652659/
https://www.ncbi.nlm.nih.gov/pubmed/31211499
http://dx.doi.org/10.1111/jcmm.14454