Modeling Pneumonic Plague in Human Precision-Cut Lung Slices Highlights a Role for the Plasminogen Activator Protease in Facilitating Type 3 Secretion

Pneumonic plague is the deadliest form of disease caused by Yersinia pestis. Key to the progression of infection is the activity of the plasminogen activator protease Pla. Deletion of Pla results in a decreased Y. pestis bacterial burden in the lung and failure to progress into the lethal proinflamm...

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Detalles Bibliográficos
Autores principales: Banerjee, Srijon K., Huckuntod, Samantha D., Mills, Shalynn D., Kurten, Richard C., Pechous, Roger D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Molecular Pathogenesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6652753/
https://www.ncbi.nlm.nih.gov/pubmed/31085709
http://dx.doi.org/10.1128/IAI.00175-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6652753/
https://www.ncbi.nlm.nih.gov/pubmed/31085709
http://dx.doi.org/10.1128/IAI.00175-19

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