A Protein E-PilA Fusion Protein Shows Vaccine Potential against Nontypeable Haemophilus influenzae in Mice and Chinchillas

PE-PilA is a fusion protein composed of immunologically relevant parts of protein E (PE) and the majority subunit of the type IV pilus (PilA), two major antigens of nontypeable Haemophilus influenzae (NTHi). Here we report on the preclinical evaluation of PE-PilA as a vaccine antigen. The immunogeni...

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Detalles Bibliográficos
Autores principales: Ysebaert, Carine, Denoël, Philippe, Weynants, Vincent, Bakaletz, Lauren O., Novotny, Laura A., Godfroid, Fabrice, Hermand, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Microbial Immunity and Vaccines
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6652774/
https://www.ncbi.nlm.nih.gov/pubmed/31109946
http://dx.doi.org/10.1128/IAI.00345-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6652774/
https://www.ncbi.nlm.nih.gov/pubmed/31109946
http://dx.doi.org/10.1128/IAI.00345-19

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