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Activation of the Endoplasmic Reticulum Stress Response Impacts the NOD1 Signaling Pathway

Nucleotide-binding oligomerization domain 1 (NOD1) is an intracellular pattern recognition receptor (PRR) responsible for sensing bacterial peptidoglycan fragments. Stimulation of NOD1 leads to a robust innate immune response via activation of the major transcription factor NF-κB. In addition to pep...

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Detalles Bibliográficos
Autores principales: Mendez, Jonathan M., Kolora, Lakshmi Divya, Lemon, James S., Dupree, Steven L., Keestra-Gounder, A. Marijke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6652781/
https://www.ncbi.nlm.nih.gov/pubmed/31109951
http://dx.doi.org/10.1128/IAI.00826-18