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SCD1 activation impedes foam cell formation by inducing lipophagy in oxLDL‐treated human vascular smooth muscle cells

The formation of fat‐laden foam cells, which contributes to the fatty streaks in the plaques of atheromas, is an important process in atherosclerosis. Vascular smooth muscle cells (VSMCs) are a critical origin of foam cells. However, the mechanisms that underlie VSMC foam cell formation are not yet...

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Detalles Bibliográficos
Autores principales: Pi, Huifeng, Wang, Zhen, Liu, Mengyu, Deng, Ping, Yu, Zhengping, Zhou, Zhou, Gao, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6652860/
https://www.ncbi.nlm.nih.gov/pubmed/31119852
http://dx.doi.org/10.1111/jcmm.14401