Cirsium japonicum var. maackii and apigenin block Hif‐2α‐induced osteoarthritic cartilage destruction

Although Hif‐2α is a master regulator of catabolic factor expression in osteoarthritis development, Hif‐2α inhibitors remain undeveloped. The aim of this study was to determine whether Cirsium japonicum var. maackii (CJM) extract and one of its constituents, apigenin, could attenuate the Hif‐2α‐indu...

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Detalles Bibliográficos
Autores principales: Cho, Chanmi, Kang, Li‐Jung, Jang, Dain, Jeon, Jimin, Lee, Hyemi, Choi, Sangil, Han, Seong Jae, Oh, Eunjeong, Nam, Jiho, Kim, Chun Sung, Park, Eunkuk, Jeong, Seon‐Yong, Park, Chan Hum, Shin, Yu Su, Eyun, Seong‐il, Yang, Siyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6652892/
https://www.ncbi.nlm.nih.gov/pubmed/31148341
http://dx.doi.org/10.1111/jcmm.14418

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6652892/
https://www.ncbi.nlm.nih.gov/pubmed/31148341
http://dx.doi.org/10.1111/jcmm.14418

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