The Natural Compound Neobractatin Induces Cell Cycle Arrest by Regulating E2F1 and Gadd45α

The complexity and multi-target feature of natural compounds have made it difficult to elucidate their mechanism of action (MoA), which hindered the development of lead anticancer compounds to some extent. In this study, we applied RNA-Seq and GSEA transcriptome analysis to rapidly and efficiently e...

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Detalles Bibliográficos
Autores principales: Zheng, Zhaoqing, Wu, Man, Zhang, Juan, Fu, Wenwei, Xu, Naihan, Lao, Yuanzhi, Lin, Lan, Xu, Hongxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6653061/
https://www.ncbi.nlm.nih.gov/pubmed/31380287
http://dx.doi.org/10.3389/fonc.2019.00654

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6653061/
https://www.ncbi.nlm.nih.gov/pubmed/31380287
http://dx.doi.org/10.3389/fonc.2019.00654

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