Cargando…

The urokinase‐type plasminogen activator system as drug target in retinitis pigmentosa: New pre‐clinical evidence in the rd10 mouse model

Retinitis pigmentosa (RP) is characterized by progressive loss of vision due to photoreceptor degeneration leading to secondary inflammation. The urokinase‐type plasminogen activator (uPA) system contributes to retinal inflammation, but its role in RP is unknown. In the rd10 mouse model of RP, we ad...

Descripción completa

Detalles Bibliográficos
Autores principales: Cammalleri, Maurizio, Dal Monte, Massimo, Locri, Filippo, Pecci, Valeria, De Rosa, Mario, Pavone, Vincenzo, Bagnoli, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6653070/
https://www.ncbi.nlm.nih.gov/pubmed/31251468
http://dx.doi.org/10.1111/jcmm.14391