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Nicorandil alleviates apoptosis in diabetic cardiomyopathy through PI3K/Akt pathway

Nicorandil exerts myocardial protection through its antihypoxia and antioxidant effects. Here, we investigated whether it plays an anti‐apoptotic role in diabetic cardiomyopathy. Sprague‐Dawley rats were fed with high‐fat diet; then single intraperitoneal injection of streptozotocin was performed. R...

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Detalles Bibliográficos
Autores principales: Wang, Xuyang, Pan, Jinyu, Liu, Dian, Zhang, Mingjun, Li, Xiaowei, Tian, Jingjing, Liu, Ming, Jin, Tao, An, Fengshuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6653072/
https://www.ncbi.nlm.nih.gov/pubmed/31131539
http://dx.doi.org/10.1111/jcmm.14413