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Sulodexide attenuates endoplasmic reticulum stress induced by myocardial ischaemia/reperfusion by activating the PI3K/Akt pathway

Acute myocardial ischaemia/reperfusion (MI/R) injury causes severe arrhythmias with a high rate of lethality. Extensive research focus on endoplasmic reticulum (ER) stress and its dysfunction which leads to cardiac injury in MI/R Our study evaluated the effects of sulodexide (SDX) on MI/R by establi...

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Detalles Bibliográficos
Autores principales: Shen, Danping, Chen, Ruiyao, Zhang, Lijing, Rao, Zhiheng, Ruan, Yongxue, Li, Lei, Chu, Maoping, Zhang, Yuanhai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6653332/
https://www.ncbi.nlm.nih.gov/pubmed/31120192
http://dx.doi.org/10.1111/jcmm.14367