Bortezomib attenuates renal interstitial fibrosis in kidney transplantation via regulating the EMT induced by TNF‐α‐Smurf1‐Akt‐mTOR‐P70S6K pathway

Allograft interstitial fibrosis was characterized by massive extracellular matrix deposition caused by activated fibroblasts and myofibroblasts. Epithelial‐mesenchymal transition (EMT) is recognized as an important source of myofibroblasts contributing to the pathogenesis of allograft interstitial f...

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Detalles Bibliográficos
Autores principales: Zhou, Jiajun, Cheng, Hong, Wang, Zijie, Chen, Hao, Suo, Chuanjian, Zhang, Hengcheng, Zhang, Jiayi, Yang, Yanhao, Geng, Liang, Gu, Ming, Tan, Ruoyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6653435/
https://www.ncbi.nlm.nih.gov/pubmed/31140729
http://dx.doi.org/10.1111/jcmm.14420

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6653435/
https://www.ncbi.nlm.nih.gov/pubmed/31140729
http://dx.doi.org/10.1111/jcmm.14420

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