Silencing of HLA class I on primary human hepatocytes as a novel strategy for reduction in alloreactivity

In contrast to the whole liver, primary hepatocytes are highly immunogenic. Thus, alternative strategies of immunomodulation after hepatocyte transplantation are of special interest. Silencing of HLA class I expression is expected to reduce the strength of allogeneic immune responses and to improve...

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Detalles Bibliográficos
Autores principales: Figueiredo, Constança, Oldhafer, Felix, Wittauer, Eva‐Maria, Carvalho‐Oliveira, Marco, Akhdar, Ali, Beetz, Oliver, Chen‐Wacker, Chen, Yuzefovych, Yuliia, Falk, Christine S., Blasczyk, Rainer, Vondran, Florian W.R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6653539/
https://www.ncbi.nlm.nih.gov/pubmed/31180181
http://dx.doi.org/10.1111/jcmm.14484

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6653539/
https://www.ncbi.nlm.nih.gov/pubmed/31180181
http://dx.doi.org/10.1111/jcmm.14484

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