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Silencing of HLA class I on primary human hepatocytes as a novel strategy for reduction in alloreactivity
In contrast to the whole liver, primary hepatocytes are highly immunogenic. Thus, alternative strategies of immunomodulation after hepatocyte transplantation are of special interest. Silencing of HLA class I expression is expected to reduce the strength of allogeneic immune responses and to improve...
Autores principales: | Figueiredo, Constança, Oldhafer, Felix, Wittauer, Eva‐Maria, Carvalho‐Oliveira, Marco, Akhdar, Ali, Beetz, Oliver, Chen‐Wacker, Chen, Yuzefovych, Yuliia, Falk, Christine S., Blasczyk, Rainer, Vondran, Florian W.R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6653539/ https://www.ncbi.nlm.nih.gov/pubmed/31180181 http://dx.doi.org/10.1111/jcmm.14484 |
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