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4‐O‐methylhonokiol protects against diabetic cardiomyopathy in type 2 diabetic mice by activation of AMPK‐mediated cardiac lipid metabolism improvement

Diabetic cardiomyopathy (DCM) is characterized by increased left ventricular mass and wall thickness, decreased systolic function, reduced ejection fraction (EF) and ultimately heart failure. The 4‐O‐methylhonokiol (MH) has been isolated mainly from the bark of the root and stem of Magnolia species....

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Detalles Bibliográficos
Autores principales: Zheng, Zongyu, Ma, Tianjiao, Guo, Hua, Kim, Ki Soo, Kim, Kyoung Tae, Bi, Liqi, Zhang, Zhiguo, Cai, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6653553/
https://www.ncbi.nlm.nih.gov/pubmed/31199069
http://dx.doi.org/10.1111/jcmm.14493