Cargando…

4‐O‐methylhonokiol protects against diabetic cardiomyopathy in type 2 diabetic mice by activation of AMPK‐mediated cardiac lipid metabolism improvement

Diabetic cardiomyopathy (DCM) is characterized by increased left ventricular mass and wall thickness, decreased systolic function, reduced ejection fraction (EF) and ultimately heart failure. The 4‐O‐methylhonokiol (MH) has been isolated mainly from the bark of the root and stem of Magnolia species....

Descripción completa

Detalles Bibliográficos
Autores principales:	Zheng, Zongyu, Ma, Tianjiao, Guo, Hua, Kim, Ki Soo, Kim, Kyoung Tae, Bi, Liqi, Zhang, Zhiguo, Cai, Lu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6653553/ https://www.ncbi.nlm.nih.gov/pubmed/31199069 http://dx.doi.org/10.1111/jcmm.14493

Ejemplares similares

Magnolia Bioactive Constituent 4-O-Methylhonokiol Prevents the Impairment of Cardiac Insulin Signaling and the Cardiac Pathogenesis in High-Fat Diet-Induced Obese Mice
por: Zhang, Zhiguo, et al.
Publicado: (2015)

The Magnolia Bioactive Constituent 4-O-Methylhonokiol Protects against High-Fat Diet-Induced Obesity and Systemic Insulin Resistance in Mice
por: Zhang, Zhiguo, et al.
Publicado: (2014)

Protective effect of the ethanol extract of Magnolia officinalis and 4-O-methylhonokiol on scopolamine-induced memory impairment and the inhibition of acetylcholinesterase activity
por: Lee, Yong Kyung, et al.
Publicado: (2009)

Methylhonokiol attenuates neuroinflammation: a role for cannabinoid receptors?
por: Gertsch, Jürg, et al.
Publicado: (2012)

Alleviation of Kainic Acid-Induced Brain Barrier Dysfunction by 4-O-Methylhonokiol in In Vitro and In Vivo Models
por: Han, Jin-Yi, et al.
Publicado: (2015)

FGF21 deletion exacerbates diabetic cardiomyopathy by aggravating cardiac lipid accumulation
por: Yan, Xiaoqing, et al.
Publicado: (2015)

4-O-Methylhonokiol Influences Normal Cardiovascular Development in Medaka Embryo
por: Singha, Santu K., et al.
Publicado: (2019)

4-O-Methylhonokiol Protects HaCaT Cells from TGF-β1-Induced Cell Cycle Arrest by Regulating Canonical and Non-Canonical Pathways of TGF-β Signaling
por: Kim, Sang-Cheol, et al.
Publicado: (2017)

Bailcalin Protects against Diabetic Cardiomyopathy through Keap1/Nrf2/AMPK-Mediated Antioxidative and Lipid-Lowering Effects
por: Li, Ran, et al.
Publicado: (2019)

2-O-Methylhonokiol Suppresses HCV Replication via TRAF6-Mediated NF-kB Activation
por: Jeong, Suyun, et al.
Publicado: (2021)

Inhibitory effect of 4-O-methylhonokiol on lipopolysaccharide-induced neuroinflammation, amyloidogenesis and memory impairment via inhibition of nuclear factor-kappaB in vitro and in vivo models
por: Lee, Young-Jung, et al.
Publicado: (2012)

Amelioration of Cognitive Dysfunction in APP/PS1 Double Transgenic Mice by Long-Term Treatment of 4-O-Methylhonokiol
por: Jung, Yu-Yeon, et al.
Publicado: (2014)

Fibroblast growth factor-21 prevents diabetic cardiomyopathy via AMPK-mediated antioxidation and lipid-lowering effects in the heart
por: Yang, Hong, et al.
Publicado: (2018)

The Protective Effect of 11-Keto-β-Boswellic Acid against Diabetic Cardiomyopathy in Rats Entails Activation of AMPK
por: AlTamimi, Jozaa Z., et al.
Publicado: (2023)

Ferroptosis is essential for diabetic cardiomyopathy and is prevented by sulforaphane via AMPK/NRF2 pathways
por: Wang, Xiang, et al.
Publicado: (2022)

Extracts of Magnolia Species-Induced Prevention of Diabetic Complications: A Brief Review
por: Zhao, Xuezhong, et al.
Publicado: (2016)

Protection against diabetic cardiomyopathy is achieved using a combination of sulforaphane and zinc in type 1 diabetic OVE26 mice
por: Wang, Jiqun, et al.
Publicado: (2019)

Diabetic Cardiomyopathy and Its Prevention by Nrf2: Current Status
por: Chen, Jing, et al.
Publicado: (2014)

Panax notoginseng Saponin Protects Against Diabetic Cardiomyopathy Through Lipid Metabolism Modulation
por: Zhang, Chenyang, et al.
Publicado: (2022)

Application of Animal Models in Diabetic Cardiomyopathy
por: Lee, Wang-Soo, et al.
Publicado: (2021)

Magnolia Extract (BL153) Protection of Heart from Lipid Accumulation Caused Cardiac Oxidative Damage, Inflammation, and Cell Death in High-Fat Diet Fed Mice
por: Sun, Weixia, et al.
Publicado: (2014)

Sensitive determination of 4-O-methylhonokiol in rabbit plasma by high performance liquid chromatography and application to its pharmacokinetic investigation
por: Li, Ming-Yue, et al.
Publicado: (2011)

Taking Diabetes to Heart—Deregulation of Myocardial Lipid Metabolism in Diabetic Cardiomyopathy
por: Bayeva, Marina, et al.
Publicado: (2013)

The New 4-O-Methylhonokiol Analog GS12021 Inhibits Inflammation and Macrophage Chemotaxis: Role of AMP-Activated Protein Kinase α Activation
por: Kim, Sora, et al.
Publicado: (2015)

Adropin Alleviates Myocardial Fibrosis in Diabetic Cardiomyopathy Rats: A Preliminary Study
por: Liu, Mao, et al.
Publicado: (2021)

Diabetic cardiomyopathy: a brief summary on lipid toxicity
por: Ke, Jiahan, et al.
Publicado: (2022)

Effects of Lespedeza Bicolor Extract on Regulation of AMPK Associated Hepatic Lipid Metabolism in Type 2 Diabetic Mice
por: Kim, Younmi, et al.
Publicado: (2019)

Neuraminidase 1 deficiency attenuates cardiac dysfunction, oxidative stress, fibrosis, inflammatory via AMPK-SIRT3 pathway in diabetic cardiomyopathy mice
por: Guo, Zhen, et al.
Publicado: (2022)

Fibroblast growth factor 21 inhibition aggravates cardiac dysfunction in diabetic cardiomyopathy by improving lipid accumulation
por: Chen, Cui, et al.
Publicado: (2018)

Spironolactone Protects against Diabetic Cardiomyopathy in Streptozotocin-Induced Diabetic Rats
por: Liu, Wenjuan, et al.
Publicado: (2018)

Dihydromyricetin Protects against Diabetic Cardiomyopathy in Streptozotocin-Induced Diabetic Mice
por: Wu, Bin, et al.
Publicado: (2017)

Diabetic cardiomyopathy: where we are and where we are going
por: Lee, Wang-Soo, et al.
Publicado: (2017)

Metformin Inhibits the NLRP3 Inflammasome via AMPK/mTOR-dependent Effects in Diabetic Cardiomyopathy
por: Yang, Fan, et al.
Publicado: (2019)

Neuregulin-4 attenuates diabetic cardiomyopathy by regulating autophagy via the AMPK/mTOR signalling pathway
por: Wang, Hongchao, et al.
Publicado: (2022)

Nomogram based on multimodal echocardiography for assessing the evolution of diabetic cardiomyopathy in diabetic patients with normal cardiac function
por: Liu, Yi, et al.
Publicado: (2022)

Iron accumulation and lipid peroxidation: implication of ferroptosis in diabetic cardiomyopathy
por: Yan, Xuehua, et al.
Publicado: (2023)

Cardiomyopathy and cardiac function in fetuses and newborns of diabetic mothers()
por: Bogo, Maria Augusta, et al.
Publicado: (2020)

Resveratrol and Diabetic Cardiomyopathy: Focusing on the Protective Signaling Mechanisms
por: Song, Yan-Jun, et al.
Publicado: (2020)

Diabetes Mellitus as a Protective Factor in Takotsubo Cardiomyopathy
por: Chhabra, Lovely
Publicado: (2023)

Protective Effects of Huangqi Shengmai Yin on Type 1 Diabetes-Induced Cardiomyopathy by Improving Myocardial Lipid Metabolism
por: Cao, Zhanhong, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_pfj58tnfsefpj67jhb8bjs01td