Immunization-Expanded NKT Follicular Helper Cells Drive IgG1 Isotype Switch against an Exogenous T-Independent Polysaccharide but Do Not Promote Recall Responses

The CD1d-binding glycolipid α-galactosylceramide (α-GC) is a potent adjuvant that activates NKT cells and in turn enhances T-dependent humoral immunity. Very little is known about how NKT cells and the NKT follicular helper (NKTfh) subset influence the immune response to T-independent polysaccharide...

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Detalles Bibliográficos
Autores principales: Lang, Gillian A., Amani, Souwelimatou Amadou, Quinn, James L., Axtell, Robert C., Lang, Mark L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6655531/
https://www.ncbi.nlm.nih.gov/pubmed/31342012
http://dx.doi.org/10.4049/immunohorizons.1800081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6655531/
https://www.ncbi.nlm.nih.gov/pubmed/31342012
http://dx.doi.org/10.4049/immunohorizons.1800081

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