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Immunization-Expanded NKT Follicular Helper Cells Drive IgG1 Isotype Switch against an Exogenous T-Independent Polysaccharide but Do Not Promote Recall Responses

The CD1d-binding glycolipid α-galactosylceramide (α-GC) is a potent adjuvant that activates NKT cells and in turn enhances T-dependent humoral immunity. Very little is known about how NKT cells and the NKT follicular helper (NKTfh) subset influence the immune response to T-independent polysaccharide...

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Detalles Bibliográficos
Autores principales:	Lang, Gillian A., Amani, Souwelimatou Amadou, Quinn, James L., Axtell, Robert C., Lang, Mark L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6655531/ https://www.ncbi.nlm.nih.gov/pubmed/31342012 http://dx.doi.org/10.4049/immunohorizons.1800081

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