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The effect of amantadine on an ion channel protein from Chikungunya virus

Viroporins like influenza A virus M2, hepatitis C virus p7, HIV-1 Vpu and picornavirus 2B associate with host membranes, and create hydrophilic corridors, which are critical for viral entry, replication and egress. The 6K proteins from alphaviruses are conjectured to be viroporins, essential during...

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Detalles Bibliográficos
Autores principales: Dey, Debajit, Siddiqui, Shumaila Iqbal, Mamidi, Prabhudutta, Ghosh, Sukanya, Kumar, Chandra Shekhar, Chattopadhyay, Soma, Ghosh, Subhendu, Banerjee, Manidipa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6655611/
https://www.ncbi.nlm.nih.gov/pubmed/31339886
http://dx.doi.org/10.1371/journal.pntd.0007548