The effects of sildenafil in maternal and fetal outcomes in pregnancy: A systematic review and meta-analysis

BACKGROUND: The number of studies associating the use of sildenafil in gestation is increasing. This drug inhibits phosphodiesterase type 5 (PDE5), an enzyme responsible for degradation of nitric oxide, and its efficacy is greater in the placental territory, as the maternal side of the placenta have...

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Detalles Bibliográficos
Autores principales: Ferreira, Raquel Domingues da Silva, Negrini, Romulo, Bernardo, Wanderley Marques, Simões, Ricardo, Piato, Sebastião
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6655684/
https://www.ncbi.nlm.nih.gov/pubmed/31339910
http://dx.doi.org/10.1371/journal.pone.0219732

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6655684/
https://www.ncbi.nlm.nih.gov/pubmed/31339910
http://dx.doi.org/10.1371/journal.pone.0219732

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