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The effects of sildenafil in maternal and fetal outcomes in pregnancy: A systematic review and meta-analysis
BACKGROUND: The number of studies associating the use of sildenafil in gestation is increasing. This drug inhibits phosphodiesterase type 5 (PDE5), an enzyme responsible for degradation of nitric oxide, and its efficacy is greater in the placental territory, as the maternal side of the placenta have...
Autores principales: | Ferreira, Raquel Domingues da Silva, Negrini, Romulo, Bernardo, Wanderley Marques, Simões, Ricardo, Piato, Sebastião |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6655684/ https://www.ncbi.nlm.nih.gov/pubmed/31339910 http://dx.doi.org/10.1371/journal.pone.0219732 |
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