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Identification of pathological RA endotypes using blood-based biomarkers reflecting tissue metabolism. A retrospective and explorative analysis of two phase III RA studies

There is an increasing demand for accurate endotyping of patients according to their pathogenesis to allow more targeted treatment. We explore a combination of blood-based joint tissue metabolites (neoepitopes) to enable patient clustering through distinct disease profiles. We analysed data from two...

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Detalles Bibliográficos
Autores principales: Blair, J. P. M., Bager, C., Platt, A., Karsdal, M., Bay-Jensen, A. -C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6655687/
https://www.ncbi.nlm.nih.gov/pubmed/31339920
http://dx.doi.org/10.1371/journal.pone.0219980