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Rescue of Rod Synapses by Induction of Ca(v) Alpha 1F in the Mature Ca(v)1.4 Knock-Out Mouse Retina
PURPOSE: Ca(v)1.4 is a voltage-gated calcium channel clustered at the presynaptic active zones of photoreceptors. Ca(v)1.4 functions in communication by mediating the Ca(2+) influx that triggers neurotransmitter release. It also aids in development since rod ribbon synapses do not form in Ca(v)1.4 k...
Autores principales: | Laird, Joseph G., Gardner, Sarah H., Kopel, Ariel J., Kerov, Vasily, Lee, Amy, Baker, Sheila A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656410/ https://www.ncbi.nlm.nih.gov/pubmed/31335952 http://dx.doi.org/10.1167/iovs.19-27226 |
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