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Adapalene Gel 0.1% Versus Placebo as Prophylaxis for Anti‐Epidermal Growth Factor Receptor‐Induced Acne‐Like Rash: A Randomized Left‐Right Comparative Evaluation (APPEARANCE)

LESSONS LEARNED. The results of the APPEARANCE trial indicate that adapalene does not prevent acne‐like rash over placebo when added to topical moisturizer and oral minocycline but instead may have a detrimental effect. Therefore, adapalene is not recommended as prophylaxis against acne‐like rash in...

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Detalles Bibliográficos
Autores principales: Chayahara, Naoko, Mukohara, Toru, Tachihara, Motoko, Fujishima, Yoshimi, Fukunaga, Atsushi, Washio, Ken, Yamamoto, Masatsugu, Nakata, Kyosuke, Kobayashi, Kazuyuki, Takenaka, Kei, Toyoda, Masanori, Kiyota, Naomi, Tobimatsu, Kazutoshi, Doi, Hisayo, Mizuta, Naomi, Marugami, Naho, Kawaguchi, Atsushi, Nishigori, Chikako, Nishimura, Yoshihiro, Minami, Hironobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656472/
https://www.ncbi.nlm.nih.gov/pubmed/30890624
http://dx.doi.org/10.1634/theoncologist.2019-0156