Extracellular vesicles derived from ODN-stimulated macrophages transfer and activate Cdc42 in recipient cells and thereby increase cellular permissiveness to EV uptake

Endosomal Toll-like receptors (TLRs) mediate intracellular innate immunity via the recognition of DNA and RNA sequences. Recent work has reported a role for extracellular vesicles (EVs), known to transfer various nucleic acids, in uptake of TLR-activating molecules, raising speculation about possibl...

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Detalles Bibliográficos
Autores principales: Zhang, Ying, Jin, Xue, Liang, Jiaqi, Guo, Yilan, Sun, Gaoge, Zeng, Xianfeng, Yin, Hang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656539/
https://www.ncbi.nlm.nih.gov/pubmed/31355328
http://dx.doi.org/10.1126/sciadv.aav1564

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656539/
https://www.ncbi.nlm.nih.gov/pubmed/31355328
http://dx.doi.org/10.1126/sciadv.aav1564

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