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Clockophagy is a novel selective autophagy process favoring ferroptosis

Ferroptosis is a form of nonapoptotic regulated cell death driven by iron-dependent lipid peroxidation. Autophagy involves a lysosomal degradation pathway that can either promote or impede cell death. A high level of autophagy has been associated with ferroptosis, but the mechanisms underpinning thi...

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Detalles Bibliográficos
Autores principales: Yang, Minghua, Chen, Pan, Liu, Jiao, Zhu, Shan, Kroemer, Guido, Klionsky, Daniel J., Lotze, Michael T., Zeh, Herbert J., Kang, Rui, Tang, Daolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656546/
https://www.ncbi.nlm.nih.gov/pubmed/31355331
http://dx.doi.org/10.1126/sciadv.aaw2238