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Plasma and CSF neurofilament light: Relation to longitudinal neuroimaging and cognitive measures

OBJECTIVE: We aimed to (1) assess and compare baseline plasma and CSF neurofilament light (NfL) for cross-sectional and longitudinal associations with neuroimaging or cognition and (2) determine whether change in plasma NfL corresponded with change in these outcomes. METHODS: Seventy-nine participan...

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Detalles Bibliográficos
Autores principales: Mielke, Michelle M., Syrjanen, Jeremy A., Blennow, Kaj, Zetterberg, Henrik, Vemuri, Prashanthi, Skoog, Ingmar, Machulda, Mary M., Kremers, Walter K., Knopman, David S., Jack, Clifford, Petersen, Ronald C., Kern, Silke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656645/
https://www.ncbi.nlm.nih.gov/pubmed/31182505
http://dx.doi.org/10.1212/WNL.0000000000007767