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Real-time PCR and targeted next-generation sequencing in the detection of low level EGFR mutations: Instructive case analyses
BACKGROUND: Allele specific real-time PCR and next-generation sequencing (NGS) are widely used to detect somatic mutation in non-small cell lung cancer (NSCLC). Both methods commonly use formalin-fixed paraffin-embedded (FFPE) tissues as diagnostic materials. Real-time PCR has the advantage of being...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656700/ https://www.ncbi.nlm.nih.gov/pubmed/31367517 http://dx.doi.org/10.1016/j.rmcr.2019.100901 |