Real-time PCR and targeted next-generation sequencing in the detection of low level EGFR mutations: Instructive case analyses

BACKGROUND: Allele specific real-time PCR and next-generation sequencing (NGS) are widely used to detect somatic mutation in non-small cell lung cancer (NSCLC). Both methods commonly use formalin-fixed paraffin-embedded (FFPE) tissues as diagnostic materials. Real-time PCR has the advantage of being...

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Detalles Bibliográficos
Autores principales: Cheng, Yu-Wei, Stefaniuk, Catherine, Jakubowski, Maureen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656700/
https://www.ncbi.nlm.nih.gov/pubmed/31367517
http://dx.doi.org/10.1016/j.rmcr.2019.100901

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