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Highly branched  poly(β-amino ester) delivery of minicircle DNA for transfection of neurodegenerative disease related cells

Current therapies for most neurodegenerative disorders are only symptomatic in nature and do not change the course of the disease. Gene therapy plays an important role in disease modifying therapeutic strategies. Herein, we have designed and optimized a series of highly branched poly(β-amino ester)s...

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Detalles Bibliográficos
Autores principales: Liu, Shuai, Gao, Yongsheng, Zhou, Dezhong, Zeng, Ming, Alshehri, Fatma, Newland, Ben, Lyu, Jing, O’Keeffe-Ahern, Jonathan, Greiser, Udo, Guo, Tianying, Zhang, Fengzhi, Wang, Wenxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656726/
https://www.ncbi.nlm.nih.gov/pubmed/31341171
http://dx.doi.org/10.1038/s41467-019-11190-0