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Highly branched poly(β-amino ester) delivery of minicircle DNA for transfection of neurodegenerative disease related cells
Current therapies for most neurodegenerative disorders are only symptomatic in nature and do not change the course of the disease. Gene therapy plays an important role in disease modifying therapeutic strategies. Herein, we have designed and optimized a series of highly branched poly(β-amino ester)s...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656726/ https://www.ncbi.nlm.nih.gov/pubmed/31341171 http://dx.doi.org/10.1038/s41467-019-11190-0 |