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Indomethacin reduces rates of aortic dissection and rupture of the abdominal aorta by inhibiting monocyte/macrophage accumulation in a murine model

Aortic dissection is a life-threatening condition, which is characterised by separation of the constituent layers of the aortic wall. We have recently shown that monocyte/macrophage infiltration into the aortic wall is a pathogenic mechanism of the condition. In the present study, we investigated wh...

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Detalles Bibliográficos
Autores principales: Tomida, Shota, Aizawa, Kenichi, Nishida, Norifumi, Aoki, Hiroki, Imai, Yasushi, Nagai, Ryozo, Suzuki, Toru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656736/
https://www.ncbi.nlm.nih.gov/pubmed/31341173
http://dx.doi.org/10.1038/s41598-019-46673-z