Synthesis and modification of uniform PEG-neridronate-modified magnetic nanoparticles determines prolonged blood circulation and biodistribution in a mouse preclinical model

Magnetite (Fe(3)O(4)) nanoparticles with uniform sizes of 10, 20, and 31 nm were prepared by thermal decomposition of Fe(III) oleate or mandelate in a high-boiling point solvent (>320 °C). To render the particles with hydrophilic and antifouling properties, their surface was coated with a PEG-con...

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Detalles Bibliográficos
Autores principales: Patsula, Vitalii, Horák, Daniel, Kučka, Jan, Macková, Hana, Lobaz, Volodymyr, Francová, Pavla, Herynek, Vít, Heizer, Tomáš, Páral, Petr, Šefc, Luděk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656745/
https://www.ncbi.nlm.nih.gov/pubmed/31341232
http://dx.doi.org/10.1038/s41598-019-47262-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656745/
https://www.ncbi.nlm.nih.gov/pubmed/31341232
http://dx.doi.org/10.1038/s41598-019-47262-w

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