Structural insights into E1 recognition and the ubiquitin-conjugating activity of the E2 enzyme Cdc34

Ubiquitin (Ub) signaling requires the sequential interactions and activities of three enzymes, E1, E2, and E3. Cdc34 is an E2 that plays a key role in regulating cell cycle progression and requires unique structural elements to function. The molecular basis by which Cdc34 engages its E1 and the stru...

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Detalles Bibliográficos
Autores principales: Williams, Katelyn M., Qie, Shuo, Atkison, James H., Salazar-Arango, Sabrina, Alan Diehl, J., Olsen, Shaun K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656757/
https://www.ncbi.nlm.nih.gov/pubmed/31341161
http://dx.doi.org/10.1038/s41467-019-11061-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656757/
https://www.ncbi.nlm.nih.gov/pubmed/31341161
http://dx.doi.org/10.1038/s41467-019-11061-8

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