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Structural insights into E1 recognition and the ubiquitin-conjugating activity of the E2 enzyme Cdc34
Ubiquitin (Ub) signaling requires the sequential interactions and activities of three enzymes, E1, E2, and E3. Cdc34 is an E2 that plays a key role in regulating cell cycle progression and requires unique structural elements to function. The molecular basis by which Cdc34 engages its E1 and the stru...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656757/ https://www.ncbi.nlm.nih.gov/pubmed/31341161 http://dx.doi.org/10.1038/s41467-019-11061-8 |