Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits

Genome-wide association studies (GWAS) have identified thousands of variants associated with complex traits, but their biological interpretation often remains unclear. Most of these variants overlap with expression QTLs, indicating their potential involvement in regulation of gene expression. Here,...

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Detalles Bibliográficos
Autores principales: Porcu, Eleonora, Rüeger, Sina, Lepik, Kaido, Santoni, Federico A., Reymond, Alexandre, Kutalik, Zoltán
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656778/
https://www.ncbi.nlm.nih.gov/pubmed/31341166
http://dx.doi.org/10.1038/s41467-019-10936-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656778/
https://www.ncbi.nlm.nih.gov/pubmed/31341166
http://dx.doi.org/10.1038/s41467-019-10936-0

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