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Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits
Genome-wide association studies (GWAS) have identified thousands of variants associated with complex traits, but their biological interpretation often remains unclear. Most of these variants overlap with expression QTLs, indicating their potential involvement in regulation of gene expression. Here,...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656778/ https://www.ncbi.nlm.nih.gov/pubmed/31341166 http://dx.doi.org/10.1038/s41467-019-10936-0 |