A Chemical Screen Identifies Compounds Capable of Selecting for Haploidy in Mammalian Cells

The recent availability of somatic haploid cell lines has provided a unique tool for genetic studies in mammals. However, the percentage of haploid cells rapidly decreases in these cell lines, which we recently showed is due to their overgrowth by diploid cells present in the cultures. Based on this...

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Detalles Bibliográficos
Autores principales: Olbrich, Teresa, Vega-Sendino, Maria, Murga, Matilde, de Carcer, Guillermo, Malumbres, Marcos, Ortega, Sagrario, Ruiz, Sergio, Fernandez-Capetillo, Oscar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656781/
https://www.ncbi.nlm.nih.gov/pubmed/31315040
http://dx.doi.org/10.1016/j.celrep.2019.06.060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656781/
https://www.ncbi.nlm.nih.gov/pubmed/31315040
http://dx.doi.org/10.1016/j.celrep.2019.06.060

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