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A Chemical Screen Identifies Compounds Capable of Selecting for Haploidy in Mammalian Cells
The recent availability of somatic haploid cell lines has provided a unique tool for genetic studies in mammals. However, the percentage of haploid cells rapidly decreases in these cell lines, which we recently showed is due to their overgrowth by diploid cells present in the cultures. Based on this...
Autores principales: | Olbrich, Teresa, Vega-Sendino, Maria, Murga, Matilde, de Carcer, Guillermo, Malumbres, Marcos, Ortega, Sagrario, Ruiz, Sergio, Fernandez-Capetillo, Oscar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656781/ https://www.ncbi.nlm.nih.gov/pubmed/31315040 http://dx.doi.org/10.1016/j.celrep.2019.06.060 |
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