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ABCE1 Controls Ribosome Recycling by an Asymmetric Dynamic Conformational Equilibrium
The twin-ATPase ABCE1 has a vital function in mRNA translation by recycling terminated or stalled ribosomes. As for other functionally distinct ATP-binding cassette (ABC) proteins, the mechanochemical coupling of ATP hydrolysis to conformational changes remains elusive. Here, we use an integrated bi...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656783/ https://www.ncbi.nlm.nih.gov/pubmed/31315050 http://dx.doi.org/10.1016/j.celrep.2019.06.052 |