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Paracellular Pathway Enhancement of Metformin Hydrochloride via Molecular Dispersion in Span 60 Microparticles

Surfactants are well known as permeation enhancers. Span 60 microparticles encapsulating different concentrations of metformin HCl were prepared by using rapid congeal melting technique. Electro-scanning microscope showed smooth surface but less round microparticles. The actual drug content was near...

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Detalles Bibliográficos
Autores principales: Mady, Omar Y., Donia, Ahmed A., Al-Shoubki, Adam A., Qasim, Waseem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656863/
https://www.ncbi.nlm.nih.gov/pubmed/31379562
http://dx.doi.org/10.3389/fphar.2019.00713