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(p)ppGpp and CodY Promote Enterococcus faecalis Virulence in a Murine Model of Catheter-Associated Urinary Tract Infection

In Firmicutes, the nutrient-sensing regulators (p)ppGpp, the effector molecule of the stringent response, and CodY work in tandem to maintain bacterial fitness during infection. Here, we tested (p)ppGpp and codY mutant strains of Enterococcus faecalis in a catheter-associated urinary tract infection...

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Detalles Bibliográficos
Autores principales: Colomer-Winter, C., Flores-Mireles, A. L., Kundra, S., Hultgren, S. J., Lemos, J. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656871/
https://www.ncbi.nlm.nih.gov/pubmed/31341072
http://dx.doi.org/10.1128/mSphere.00392-19