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Administration of Tramadol or Buprenorphine via the drinking water for post-operative analgesia in a mouse-osteotomy model
Adequate analgesia is essential whenever pain might occur in animal experiments. Unfortunately, the selection of suitable analgesics for mice in bone-linked models is limited. Here, we evaluated two analgesics – Tramadol [0.1 mg/ml (T(low)) vs. 1 mg/ml (T(high))] and Buprenorphine (Bup; 0.009 mg/ml)...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656891/ https://www.ncbi.nlm.nih.gov/pubmed/31341225 http://dx.doi.org/10.1038/s41598-019-47186-5 |