CS-PEI/Beclin-siRNA Downregulate Multidrug Resistance Proteins and Increase Paclitaxel Therapeutic Efficacy against NSCLC

Paclitaxel (PTX) is a widely used chemotherapy drug; however, frequent use causes multidrug resistance (MDR), which limits the utility of PTX against advanced non-small-cell lung cancer (NSCLC). PTX-resistant subline (NCI-H23-TXR) was established in vitro by exposing NCI-H23 cells to gradually incre...

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Detalles Bibliográficos
Autores principales: Liu, Wangta, Lo, Yu-Lun, Hsu, Chin, Wu, Yi-Ting, Liao, Zi-Xian, Wu, Wen-Jeng, Chen, Yi-Jou, Kao, Chieh, Chiu, Chien-Chih, Wang, Li-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656922/
https://www.ncbi.nlm.nih.gov/pubmed/31336235
http://dx.doi.org/10.1016/j.omtn.2019.06.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656922/
https://www.ncbi.nlm.nih.gov/pubmed/31336235
http://dx.doi.org/10.1016/j.omtn.2019.06.017

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