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CS-PEI/Beclin-siRNA Downregulate Multidrug Resistance Proteins and Increase Paclitaxel Therapeutic Efficacy against NSCLC
Paclitaxel (PTX) is a widely used chemotherapy drug; however, frequent use causes multidrug resistance (MDR), which limits the utility of PTX against advanced non-small-cell lung cancer (NSCLC). PTX-resistant subline (NCI-H23-TXR) was established in vitro by exposing NCI-H23 cells to gradually incre...
Autores principales: | Liu, Wangta, Lo, Yu-Lun, Hsu, Chin, Wu, Yi-Ting, Liao, Zi-Xian, Wu, Wen-Jeng, Chen, Yi-Jou, Kao, Chieh, Chiu, Chien-Chih, Wang, Li-Fang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656922/ https://www.ncbi.nlm.nih.gov/pubmed/31336235 http://dx.doi.org/10.1016/j.omtn.2019.06.017 |
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