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Epigenome-wide association study of asthma and wheeze characterizes loci within HK1

BACKGROUND: To identify novel epigenetic markers of adolescent asthma and replicate findings in an independent cohort, then explore whether such markers are detectable at birth, predictive of early-life wheeze, and associated with gene expression in cord blood. METHODS: We performed epigenome-wide s...

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Detalles Bibliográficos
Autores principales: Everson, Todd M., Zhang, Hongmei, Lockett, Gabrielle A., Kaushal, Akhilesh, Forthofer, Melinda, Ewart, Susan L., Burrows, Kimberley, Relton, Caroline L., Sharp, Gemma C., Henderson, A. John, Patil, Veeresh K., Rezwan, Faisal I., Arshad, S. Hasan, Holloway, John W., Karmaus, Wilfried
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657035/
https://www.ncbi.nlm.nih.gov/pubmed/31367216
http://dx.doi.org/10.1186/s13223-019-0356-z