Insertion/deletion-activated frame-shift fluorescence protein is a sensitive reporter for genomic DNA editing

BACKGROUND: Reporter methods to quantitatively measure the efficiency and specificity of genome editing tools are important for the development of novel editing techniques and successful applications of available ones. However, the existing methods have major limitations in sensitivity, accuracy, an...

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Detalles Bibliográficos
Autores principales: Kumar, Akhilesh, Birnbaum, Michael D., Moorthy, Balaji T., Singh, Jayanti, Palovcak, Anna, Patel, Devang M., Zhang, Fangliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657097/
https://www.ncbi.nlm.nih.gov/pubmed/31340764
http://dx.doi.org/10.1186/s12864-019-5963-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657097/
https://www.ncbi.nlm.nih.gov/pubmed/31340764
http://dx.doi.org/10.1186/s12864-019-5963-z

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