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Insertion/deletion-activated frame-shift fluorescence protein is a sensitive reporter for genomic DNA editing
BACKGROUND: Reporter methods to quantitatively measure the efficiency and specificity of genome editing tools are important for the development of novel editing techniques and successful applications of available ones. However, the existing methods have major limitations in sensitivity, accuracy, an...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657097/ https://www.ncbi.nlm.nih.gov/pubmed/31340764 http://dx.doi.org/10.1186/s12864-019-5963-z |