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Parallel Induction of CH505 B Cell Ontogeny-Guided Neutralizing Antibodies and tHIVconsvX Conserved Mosaic-Specific T Cells against HIV-1

The aim of this work was to start collecting information on rational combination of antibody (Ab) and T cell vaccines into single regimens. Two promising candidate HIV-1 vaccine strategies, sequential isolates of CH505 virus Envs developed for initiation of broadly neutralizing antibody lineages and...

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Detalles Bibliográficos
Autores principales: Wee, Edmund G., Moyo, Nathifa A., Saunders, Kevin O., LaBranche, Celia, Donati, Filippo, Capucci, Silvia, Parks, Robert, Borthwick, Nicola, Hannoun, Zara, Montefiori, David C., Haynes, Barton F., Hanke, Tomáš
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657236/
https://www.ncbi.nlm.nih.gov/pubmed/31367651
http://dx.doi.org/10.1016/j.omtm.2019.06.003