Microarray gene profiling analysis of glioblastoma cell line U87 reveals suppression of the FANCD2/Fanconi anemia pathway by the combination of Y15 and temozolomide

INTRODUCTION: A recent study showed that a combination of Y15 (a FAK autophosphorylation inhibitor) with temozolomide (TMZ) treatment was effective in glioblastoma (GBM) therapy. In this study, we further investigated the pathways and genes that are differentially expressed in Y15 and TMZ treated U8...

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Detalles Bibliográficos
Autores principales: Wang, Zichuan, Chen, Nan, Yang, Jin, Wang, Qingzhong, Li, Aimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2019
Materias:
Basic Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657253/
https://www.ncbi.nlm.nih.gov/pubmed/31360198
http://dx.doi.org/10.5114/aoms.2019.86063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657253/
https://www.ncbi.nlm.nih.gov/pubmed/31360198
http://dx.doi.org/10.5114/aoms.2019.86063

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