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Role of epigenetic modifications in the aberrant CYP19A1 gene expression in polycystic ovary syndrome

INTRODUCTION: In this study, the global DNA methylation, histone acetylation and methylation levels of cumulus cells (CCs) in infertile polycystic ovary syndrome (PCOS) patients and the correlation of these epigenetic modifications with the expression of the ovarian aromatase gene (as an important m...

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Detalles Bibliográficos
Autores principales: Hosseini, Elham, Shahhoseini, Maryam, Afsharian, Parvaneh, Karimian, Leila, Ashrafi, Mahnaz, Mehraein, Fereshteh, Afatoonian, Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657255/
https://www.ncbi.nlm.nih.gov/pubmed/31360184
http://dx.doi.org/10.5114/aoms.2019.86060